The life cycle of Plasmodium is digenetic, involving two hosts: the female Anopheles mosquito (definitive host) and humans (intermediate host).
Sexual reproduction (gametogamy and syngamy) occurs exclusively within the gut of the female Anopheles mosquito. The gametocytes, which are formed in human blood, are ingested by the mosquito during a blood meal.
Option (A) is correct because fertilization (fusion of gametes) occurs in the mosquito gut. Option (B) and (C) are incorrect because sexual reproduction does not occur in human liver cells or RBCs; these sites are for asexual multiplication (schizogony). Option (D) is incorrect because gametocytes develop in human blood, not the mosquito gut.
Final Answer: (A)
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