The Bacillus thuringiensis (Bt) bacterium produces insecticidal crystal proteins known as Cry proteins. These proteins exist in an inactive protoxin form within the bacterium.
When an insect ingests the inactive Bt toxin, it enters the midgut of the insect. The midgut environment of the target insect is characterized by a high alkaline pH.
The alkaline pH of the gut solubilizes the crystals, allowing the inactive protoxin to be converted into its active toxic form. This active toxin then binds to the epithelial cells of the midgut, causing cell lysis and eventually the death of the insect.
Final Answer: due to alkaline pH
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